Plasma N-acetyl-?,D-glucosaminidase activities and glycaemia in diabetes mellitus

Urinary Activities of N-acetyl-β-D-glucosaminidase and Its Isoenzyme B in Cadmium-Exposed Rats

This paper aims to assess the relationship between the urinary activity of N-acetyl-β-D-glucosaminidase (NAG) and its isoenzyme B (NAG-B) and cadmium (Cd) concentration in the urine as well as to evaluate which of these lysosomal enzymes may be a more useful biomarker for the monitoring of Cd-induced tubular damage. For this purpose we have used an experimental model in rats chronically exposed...

Is urinary N-acetyl-beta-D-glucosaminidase a marker of urological abnormality in children?

  Abstract   Background: Hydronephrosis is the most common congenital condition that is detected   by prenatal ultrasonography. Moreover, the widespread use of prenatal ultrasonography   results in an increased recognition of fetal hydronephrosis. Prenatal hydronephrosis   is diagnosed at an incidence of 1:100 to 1:500 by ultrasonographic studies. The presence of hydronephrosis is not synonymou...

Studies on glucosaminidase; N-acetyl-beta-glucosaminidase in rat kidney.

Studies on glucosaminidase. 2. Substrates for N-acetyl-beta-glucosaminidase.

the oxygen uptake and acetoacetate oxidation when added alone or with fumarate, but not in the presence of a-oxoglutarate. The reasons for these differences are discussed. Anaerobically, relatively slight inhibitions of the reduction of acetoacetate were observed. 6. The oxidation of L( + )-p-hydroxybutyrate is inhibited by dinitrophenol, whereas that of the D(-)-form is not. This is related to...

SpectrophotometricAssayfor UrinaryN-Acetyl-f3-D-Glucosaminidase Activity

An improved assay for N-acetyl-/3-o-glucosaminidase activity in urine is described that involves (a) gel filtration to separate the enzyme from inhibitors in urine, (b) enzymic hydrolysis of p-nitrophenyl-N-acetyl-3-D-glucosaminide at pH 4.4, and (C) spectrophotometry of the liberated p-nitrophenylate. Measurements of activity of the enzyme in 58 urine specimens correlated closely (r = 0.9998) ...